Effect of intrastrain variation in the amount of capsular polysaccharide on genetic transformation of Streptococcus pneumoniae: implications for virulence studies of encapsulated strains.
نویسندگان
چکیده
The degrees of competence of opaque and transparent colony variants of Streptococcus pneumoniae were compared. The transparent variants were transformed at 9- to 670-fold-higher rates than the opaque variants, independent of the DNA incorporated, due to decreased expression of capsular polysaccharide. Genetic transformation, therefore, tends to select for a less-encapsulated subpopulation.
منابع مشابه
Risk factors for the misdiagnosis of tuberculosis in the UK, 2001-2011.
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عنوان ژورنال:
- Infection and immunity
دوره 67 7 شماره
صفحات -
تاریخ انتشار 1999